Takako Saeki Selected Research

Immunoglobulin G4-Related Disease

1/2024	Improved Renal Function in Initial Treatment Improves Patient Survival, Renal Outcomes, and Glucocorticoid-Related Complications in IgG4-Related Kidney Disease in Japan.
1/2022	Distinct disease-specific Tfh cell populations in 2 different fibrotic diseases: IgG4-related disease and Kimura disease.
1/2021	Hypocomplementemia is related to elevated serum levels of IgG subclasses other than IgG4 in IgG4-related kidney disease.
5/2020	Impaired expression of innate immunity-related genes in IgG4-related disease: A possible mechanism in the pathogenesis of IgG4-RD.
12/2019	Clinical and Pathological Characteristics of IgG4-Related Periaortitis/Periarteritis and Retroperitoneal Fibrosis Diagnosed Based on Experts' Diagnosis.
9/2019	IgG4-related disease in the Japanese population: a genome-wide association study.
3/2019	IgG4-related kidney disease and retroperitoneal fibrosis: An update.
9/2018	Comparison of clinical and laboratory features of patients with and without allergic conditions in IgG4-related disease: A single-center experience in Japan.
3/2018	Diagnostic sensitivity of cutoff values of IgG4-positive plasma cell number and IgG4-positive/CD138-positive cell ratio in typical multiple lesions of patients with IgG4-related disease.
1/2018	The expansion in lymphoid organs of IL-4+ BATF+ T follicular helper cells is linked to IgG4 class switching in vivo.

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Takako Saeki Research Topics

Disease

29	Immunoglobulin G4-Related Disease 01/2024 - 11/2010
15	Interstitial Nephritis (Tubulointerstitial Nephritis) 03/2023 - 06/2007
11	Fibrosis (Cirrhosis) 01/2022 - 06/2007
6	Rheumatoid Arthritis 01/2016 - 01/2009
4	Infections 01/2024 - 12/2004
4	Neoplasms (Cancer) 01/2024 - 10/2003
4	Kidney Diseases (Kidney Disease) 01/2024 - 12/2011
4	Autoimmune Pancreatitis 10/2011 - 01/2006
3	Glomerulonephritis 12/2023 - 02/2004
3	Vasculitis (Vasculitides) 03/2023 - 02/2004
3	Chronic Renal Insufficiency 08/2020 - 01/2010
3	Inflammation (Inflammations) 03/2019 - 01/2006
3	Amyloidosis 01/2016 - 06/2009
3	Membranous Glomerulonephritis (Membranous Nephropathy) 03/2015 - 05/2014
3	Disease Progression 07/2014 - 02/2011
2	Autoimmune Diseases (Autoimmune Disease) 09/2019 - 01/2013
2	Fanconi Syndrome (Syndrome, Fanconi) 09/2018 - 12/2017
2	Eosinophilia 09/2018 - 01/2015
2	Hypertension (High Blood Pressure) 06/2018 - 03/2006
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 04/2017 - 06/2009
2	Chronic Kidney Failure (Chronic Renal Failure) 02/2016 - 01/2011
2	Renal Insufficiency (Renal Failure) 05/2014 - 02/2014
2	Pleural Effusion (Pleural Effusions) 01/2013 - 02/2011
2	Thrombocytopenia (Thrombopenia) 01/2013 - 12/2004
2	Proteinuria 06/2006 - 03/2006
1	Cryopyrin-Associated Periodic Syndromes 01/2024
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2024
1	Purpura 12/2023
1	Churg-Strauss Syndrome (Allergic Angiitis) 12/2023
1	Peripheral Nervous System Diseases (PNS Diseases) 12/2023
1	Myositis (Idiopathic Inflammatory Myopathies) 09/2023
1	Autoimmune Polyendocrinopathies (Schmidt Syndrome) 09/2023
1	Systemic Scleroderma (Systemic Sclerosis) 09/2023
1	Sclerosis 09/2023
1	Thyroid Diseases (Thyroid Disease) 09/2023
1	Rheumatic Diseases (Rheumatism) 09/2023
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 09/2023
1	Sinus Histiocytosis (Rosai-Dorfman Disease) 03/2023
1	Multi-centric Castleman's Disease 03/2023
1	Kimura Disease 01/2022
1	Hyperphosphatemia 08/2020
1	Dysbiosis 08/2020
1	Paraproteinemias (Monoclonal Gammopathy) 12/2019
1	Monoclonal Gammopathy of Undetermined Significance 12/2019
1	Cicatrix (Scar) 03/2019
1	Hypersensitivity (Allergy) 09/2018
1	Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome) 06/2018
1	Renal Tubular Acidosis (Distal Renal Tubular Acidosis) 12/2017
1	Body Weight (Weight, Body) 09/2017
1	Chronic recurrent multifocal osteomyelitis 09/2017
1	Vascular Skin Diseases 04/2017

Drug/Important Bio-Agent (IBA)

28	Immunoglobulin G (IgG)IBA 01/2022 - 01/2006
9	TinIBA 03/2019 - 06/2007
8	Immunoglobulins (Immunoglobulin)IBA 01/2024 - 01/2010
8	GlucocorticoidsIBA 01/2024 - 06/2009
5	AutoantibodiesIBA 09/2023 - 02/2004
5	SteroidsIBA 05/2020 - 06/2009
4	AntibodiesIBA 09/2018 - 01/2015
4	AA amyloidosisIBA 01/2016 - 11/2009
4	Adrenal Cortex Hormones (Corticosteroids)IBA 07/2014 - 11/2010
3	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 12/2023 - 02/2004
3	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2015
3	Immunoglobulin E (IgE)IBA 01/2022 - 11/2010
3	DNA (Deoxyribonucleic Acid)IBA 05/2020 - 01/2015
3	Prednisolone (Predate)FDA LinkGeneric 09/2017 - 06/2006
3	Amyloid (Amyloid Fibrils)IBA 01/2016 - 01/2011
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2013 - 01/2009
2	Peroxidase (Myeloperoxidase)IBA 12/2023 - 02/2004
2	Interleukin-13IBA 01/2022 - 01/2015
2	Interleukin-10 (Interleukin 10)IBA 01/2022 - 01/2015
2	CytokinesIBA 01/2022 - 01/2015
2	Capsules (Microcapsules)IBA 03/2019 - 07/2012
2	CreatinineIBA 06/2018 - 11/2013
2	CollagenIBA 01/2016 - 01/2015
2	Proteins (Proteins, Gene)FDA Link 05/2014 - 01/2013
1	canakinumab FDA Link 01/2024
1	InterleukinsIBA 01/2024
1	Interleukin-1 (Interleukin 1)IBA 01/2024
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 12/2023
1	Hormones (Hormone)IBA 09/2023
1	Rituximab (Mabthera)FDA Link 09/2023
1	sucroferric oxyhydroxideIBA 08/2020
1	Uremic ToxinsIBA 08/2020
1	IndicanIBA 08/2020
1	Sulfates (Sulfates, Inorganic)IBA 08/2020
1	Secretory Leukocyte Peptidase InhibitorIBA 05/2020
1	Transcobalamins (Transcobalamin II)IBA 05/2020
1	bactericidal permeability increasing proteinIBA 05/2020
1	LactoferrinIBA 05/2020
1	Immunoglobulin A (IgA)IBA 12/2019
1	HLA-DRB1 Chains (HLA DRB1)IBA 09/2019
1	Peptides (Polypeptides)IBA 09/2019
1	Diphosphonates (Bisphosphonates)IBA 06/2018
1	Interleukin-4 (Interleukin 4)IBA 01/2018
1	Immunoglobulin M (IgM)IBA 12/2017
1	tocilizumab (atlizumab)FDA Link 09/2017
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 04/2017

Therapy/Procedure

13	Therapeutics 12/2023 - 06/2009
4	Renal Dialysis (Hemodialysis) 08/2020 - 01/2011
2	Aftercare (After-Treatment) 01/2024 - 02/2016